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Chlorella Health Benefits

 

Chlorella Chlorella is a single celled green algae and has been on earth for more than 3 billion years. It is one of the most widely studied food supplement because of its various health benefits. Some of the health benefits of chlorella are:

Chlorella as a Detoxification Agent

Chlorella is a food supplement with high chlorophyll content that can detoxify our body. It helps in removing all toxins and other heavy metals including mercury from our body. Several clinical studies and researches have found that chlorella is a powerful detoxification agent. Some of them are:

  • A study carried out by Shim, Jae-Young et al., Department of Food and Nutrition, Hanyang University, Republic of Korea, showed that chlorella is effective in eliminating cadmium from the liver of rats… (See here).
  • Another study carried out by Uchikawa et al., Chlorella Industry Co. Ltd, Japan, showed that there was an increased excretion of lead in mice treated with chlorella powder… (View more).
  • Clinical studies and medical researches conducted by Dr. David Steenblock, President, Aging Research Institute, Chlorella Natural Medicine Algae, Mission Viejo, CA 1996, has found that toxins such as arsenic, mercury, lead, pesticides, insecticides, cadmium, uranium, etc., have been successfully detoxified from the human body by chlorella… (More).
  • Research studies done by Adrian Cooper, a famous author and researcher, in 2014, has shown that chlorella is the ultimate detoxification food capable of removing toxic metals, including mercury… (More).
  • Studies by Shiro Nakano et al., Saiseikai Nara Hospital, Japan, have found that Chlorella pyrenoidosa supplements given to pregnant women significantly reduced total dioxins levels in breast milk and thus suggest that maternal transfer of dioxins can be reduced using dietary measures such as Chlorella supplements. (More)
  • In a study conducted by K Morita et al., Fukuoka Institute of Health and Environmental Sciences, Dazaifu City, Japan, the effects of chlorophyll extracted from chlorella on gastrointestinal absorption of polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) in rats were observed. They were fed with 4 g chlorophyll diet containing 0.01-0.05% chlorophyll. Results showed that chlorophyll from chlorella decreased the amount of PCDD and PCDF significantly. (More).

 

Chlorella for Heart Health

Chlorella plays a major role in protecting cardiovascular function. Many researches have found how chlorella protects the heart in various ways. Some of the features are:

  • A double-blinded, randomized study conducted by Na Hee Ryu et al., Ewha Womans University, Republic of Korea, found that a daily 5g dose of chlorella was associated with significant reductions in those factors associated with heart risk and also increase in carotenoids… (Know more).
  • In another study conducted by Wong JC et al.,University of Georgia, Athens, GA, USA, after chlorella supplement, there was significant decrease in the level of total cholesterol and triglycerides while there was an increase in levels of antioxidants lutein and zeaxanthin. There was also reduction in the levels of VLDL cholesterol, non-high density lipoprotein and apolipoprotein… (More from here).
  • A study conducted by Takeshi Otsuki et al., Ryutsu Keizai University, Japan, suggest that multicomponent supplement containing chlorella can significantly reduce arterial stiffness which is a cardiovascular risk factor… (see text).
  • Clinical studies conducted by Randall E. Merchant et al., Department of Anatomy and Internal Medicine, Virginia Commonwealth University, Virginia, showed that chlorella helped in decreasing hypertension , which ultimately reduced the risk of heart disease… (More).

 

Chlorella for Cancer

Research studies have shown that chlorella is effective in treating cancer.

  • A recent study conducted by Naoto Noguchi et al., Research Laboratory, Chlorella Industry Co., Ltd., Japan, has found that chlorella has beneficial effects on the quality of life of people with breast cancer. People were found to have reduced fatigue when given supplements of chlorella … (More).
  • Research conducted by G. L. Renju et al., Department of Biochemistry, University of Kerala, Trivandrum, has shown that lycopene isolated from chlorella has positive effects on the treatment of prostate cancer. Algal lycopene showed very significant anti-proliferative and apoptotic effect in human prostate cancer cell lines… (Know more).
  • Studies by Kwang Hyun Cha et al., Natural Products Research Center, Korea, has found that semipurified extracts of C. ellipsoideaand C. vulgaris inhibited HCT116 cell growth in a dose-dependent manner, yielding IC50values of 40.73 ± 3.71 and 40.31 ± 4.43 μg/mL, respectively. In addition, treatment with both chlorella extracts enhanced the fluorescence intensity of the early apoptotic cell population in HCT116 cells. C. ellipsoidea extract produced an apoptosis-inducing effect almost 2.5 times stronger than that of the C. vulgaris extract. These results indicate that bioactive xanthophylls of C. ellipsoidea might be useful functional ingredients in the prevention of human cancers. (More)
  • Research by Kuniaki Tanaka et al., Research Laboratories, Chlorella Industries co.Ltd., Japan, have found that a glycoprotein extract (CVS), derived from the unicellular green alga Chlorella vulgaris, strain CK22, exhibited a pronounced antitumor effect against both spontaneous and experimentally induced metastasis. Inhibition of tumor metastasis was enhanced when intratumor administration of CVS was followed by s.c. injection of CVS. The antitumor activity of CVS was reflected in antigen-specific, T-cell-mediated immunity. Both CD4 and CD8 T cells contributed to the antimetastatic effects, as shown by in vivo depletion experiments with anti-T-cell subset antibodies. (More)
  • Research by Yasmin Anum Mohd Yusof et al., Department of Biochemistry, Malaysia, have found that Chlorella vulgaris decreased the number of viable HepG2 cells in a dose dependent manner when HepG2 liver cancer cells and WRL68 normal liver cells were treated with various concentrations (0-4 mg/ml) of hot water extract of C. vulgaris after 24 hours incubation. Thus Chlorella may have anti-cancer effects. (More)
  • Jing-Gung Chung et al., Department of Biological Science and Technology, Taiwan, ROC, conducted an experiment where The effects of 80% ethanolic extract derived from commercial granule chlorella (GPE) on cell viability, invasion capacity and apoptosis in human hepatoma cell line (Hep G2 cells) were investigated. The results demonstrated that GPE decreased cell viability, induced apoptosis and showed invasion inhibitory effects in the Hep G2 cells. (More)
  • Studies by Suhaniza Sulaiman et al., Department of Biochemistry, Malaysia, have shown that liver cancer induced rats when treated with Chlorella vulgaris for 8 to 12 weeks, they showed increased levels of super oxide dismutase (SOD), glutathi0ne peroxidase (GPx) and malondialdehyde  (MDA). Thus Chlorella vulgaris may have a protective role in liver cancer induced rats by compensating the activities of antioxidant enzymes and by reducing lipid peroxidation. (More)
  • In a study by LI YAN-JUN et al., Department of Biochemistry and Molecular Biology, China, a gene of Chlorella vulgaris CvFad3 was made to express in a eukaryotic expression vector to form a recombinant and it was transfected into breast cancer cell MCF-7. The results showed that the gene CvFad3 of Chlorella vulgaris can express in human breast cancer cells MCF-7 heterologously and inhibit proliferation of MCF-7 cells. (More)
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    Chlorella – A Supplement for Diabetes

    Many research studies have found that chlorella is very effective for treating diabetes.

    • Solazyme, a San Francisco Bay Area green tech company and the University of Manitoba has secured a patent for the use of a strain of microalgae called Chlorella protothecoides to treat people with impaired glucose tolerance and diabetes… (More)

     

    Chlorella and UV radiation

    • Studies by Chiu-Lan Chen et al., Department of Pharmacy, Taiwan have found that Chlorella inhibit UVB-induced MMP-1 level. Chlorella derived peptide (CDP) was added to skin fibroblasts after UVB irradiation and the expression of MMP-1, CYR61, procollagen, c-fos, c-jun, and TGF-β receptor (TbRII) mRNA and MCP-1 production were investigated. Results show that CDP inhibits UVB-induced MMP-1 expression in skin fibroblasts by suppressing expression of AP-1 and CYR61 and MCP-1 production. (More)

     

    Chlorella and enzyme activities

    • A Chlorella powder was tested in 118 in vitro enzyme assay systems. The powder showed potent inhibitions of peptidase cathepsin S, thromboxane A2 synthase and cyclooxygenase-2 in a dose-concentration manner. The actions to inhibit cyclooxygenase-2 and thromboxane synthase could contribute to the purported anti-inflammatory and anti-thrombotic effects of Chlorella. These results reveal important potential biochemical activities to be developed that, if confirmed by in vivo studies, might be exploited for the prevention or treatment of several serious pathologies, including inflammatory diseases, immune and cancer. The study was conducted by Fong-Chi Cheng et al., MDS Pharma Services Taiwan, Ltd, China (More)

     

    Chlorella as an antioxidant

    • Studies by Sun Hee Lee et al., Department of Medical Nutrition, Korea, have shown that 6.3 g of Chlorella supplementation for 6 weeks in 52 smokers,  increased plasma vitamin C, α-tocopherol,  and erythrocyte catalase and superoxide dismutase activities. There was also significant decrease in lymphocyte DNA damage, as measured by comet assay. (More)

     

    Chlorella and Immune function

    Chlorella and Non-Alcoholic Fatty Liver Disease

    • Studies by Farzad Kakaie3 et al.,  Department of Surgery, Tabriz University of Medical Sciences, Iran, have found that 70 NAFLD patients when given four 300 mg tablets of Chlorella vulgaris  for 8 weeks, their weight,  serum alanine aminotransferase (ALT), and alkaline phosphatase (ALP) levels significantly decreased. There was also significant reduction in aspartate aminotransferase (AST) and hs-CRP levels. (More)

     

    Chlorella for Brain Health

    • In a study conducted by HyeJun Yun et al., Dept. of Food and Nutrition, Hanyang University, rats exposed to the toxic heavy metal lead, were given 2, 5 or 10% Chlorella vulgaris for 4 weeks. The results showed that Chlorella vulgaris increased the levels of oxidative stress parameters in the brain such as superoxide dismutase, glutathione peroxidase and glutathione reductase. (More)

     Chlorella for Liver Health

    • In a study conducted by Jae-Young Shim et al., Department of Food and Nutrition, South Korea, cadmium induced rats when supplemented with 5% or 10% chlorella, they showed higher metallothioneins in the liver stating that Chlorella vulgaris would have a protective effect on cadmium-treated liver injury by the reduction of cadmium concentrations and stimulation of Cd-MT binds in the liver. (More)
    • In a study conducted by Jose Azocar et al., Northgate Medical Center, United States, 18 adults with chronic infection by Hepatitis C virus genotype I received daily oral supplementation of chlorella for 12 weeks. The results showed that a majority of patients had a significant decrease in their alanine aminotransferase (ALT) levels. They also reported an improvement in their energy levels and also an improvement in their perception of general health. (More)
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